Literature summary for 2.3.2.2 extracted from

Roux, F.; Durieu-Trautmann, O.; Chaverot, N.; Claire, M.; Mailly, P.; Bourre, J.M.; Strosberg, A.D.; Couraud, P.O.
Regulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells (1994), J. Cell. Physiol., 159, 101-113.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
additional information	blood-brain-barrier-associated isozyme	Rattus norvegicus	-	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	microvessel of endothelial cells, immortalized cell line	Rattus norvegicus	-
cell culture	-	Rattus norvegicus	-
additional information	blood-brain-barrier-associated isozyme activity induces the cell to form three-dimensional structures in cell culture, inducible by angiogenic and astroglial factors, e.g. bFGF, formation is reduced by cAMP	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(5-L-glutamyl)-peptide + acceptor + H+	-	Rattus norvegicus	peptide + 5-L-glutamyl amino acid	-	?

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Release 2023.1 (January 2023)