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Literature summary for 2.3.2.18 extracted from

  • Nega, M.; Dube, L.; Kull, M.; Ziebandt, A.K.; Ebner, P.; Albrecht, D.; Krismer, B.; Rosenstein, R.; Hecker, M.; Goetz, F.
    Secretome analysis revealed adaptive and non-adaptive responses of the Staphylococcus carnosus femB mutant (2015), Proteomics, 15, 1268-1279.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N6-tri-Gly)-D-Ala-D-Ala-diphospho-ditrans,octacis-undecaprenyl-GlcNAc + glycyl-tRNAGly Staphylococcus carnosus
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MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N6-penta-Gly)-D-Ala-D-Ala-diphospho-ditrans,octacis-undecaprenyl-GlcNAc + tRNAGly
-
?
MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N6-tri-Gly)-D-Ala-D-Ala-diphospho-ditrans,octacis-undecaprenyl-GlcNAc + glycyl-tRNAGly Staphylococcus carnosus TM300
-
MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N6-penta-Gly)-D-Ala-D-Ala-diphospho-ditrans,octacis-undecaprenyl-GlcNAc + tRNAGly
-
?

Organism

Organism UniProt Comment Textmining
Staphylococcus carnosus
-
-
-
Staphylococcus carnosus TM300
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N6-tri-Gly)-D-Ala-D-Ala-diphospho-ditrans,octacis-undecaprenyl-GlcNAc + glycyl-tRNAGly
-
Staphylococcus carnosus MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N6-penta-Gly)-D-Ala-D-Ala-diphospho-ditrans,octacis-undecaprenyl-GlcNAc + tRNAGly
-
?
MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N6-tri-Gly)-D-Ala-D-Ala-diphospho-ditrans,octacis-undecaprenyl-GlcNAc + glycyl-tRNAGly
-
Staphylococcus carnosus TM300 MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N6-penta-Gly)-D-Ala-D-Ala-diphospho-ditrans,octacis-undecaprenyl-GlcNAc + tRNAGly
-
?

Synonyms

Synonyms Comment Organism
FemABX peptidyl transferase
-
Staphylococcus carnosus
FemB
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Staphylococcus carnosus

General Information

General Information Comment Organism
malfunction a Staphylococcus carnosus femB deletion mutant is affected in growth and shows pleiotropic effects such as enhanced methicillin sensitivity, lysostaphin resistance, cell clustering, and decreased peptidoglycan crosslinking Staphylococcus carnosus