Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli Rosetta 2 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
G224V | the mutation increases the enzyme's calcium-binding affinity and transamidation activity 10fold and isopeptidase activity severalfold | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.9 | - |
alpha2 plasmin inhibitor | at pH 7.5 and 37°C | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | dependent on | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
[protein]-L-glutamine + alkylamine | Homo sapiens | - |
[protein]-N5-alkyl-L-glutamine + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P21980 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-aminobenzoyl-APE(gamma-Cad-2,4-dinitrophenyl)QEA + Gly-OMe | - |
Homo sapiens | ? | - |
? | |
5-(biotinamido)pentylamine + N,N-dimethylated casein | - |
Homo sapiens | ? + NH3 | - |
? | |
alpha2 plasmin inhibitor + ? | - |
Homo sapiens | ? | - |
? | |
[protein]-L-glutamine + alkylamine | - |
Homo sapiens | [protein]-N5-alkyl-L-glutamine + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TG2 | - |
Homo sapiens |
transglutaminase 2 | - |
Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
45 | - |
melting temperature | Homo sapiens |