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Literature summary for 2.3.2.13 extracted from

  • Case, A.; Stein, R.L.
    Kinetic analysis of the action of tissue transglutaminase on peptide and protein substrates (2003), Biochemistry, 42, 9466-9481.
    View publication on PubMed
Search for more literature for 2.3.2.13

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0019
-
 Dansylcadaverine pH 7.4, 30°C Cavia porcellus
0.0033
-
 N-methyl-casein pH 7.4, 30°C Cavia porcellus
1.8
-
 Z-Gln-Gly pH 7.4, 30°C Cavia porcellus

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-
Homo sapiens
-
-
-

Reaction

Reaction Comment Organism Reaction ID
protein glutamine + alkylamine = protein N5-alkylglutamine + NH3 complex kinetic mechanism with substrate Z-Gln-Gly involving Gln hydrolysis, intramolecular transpeptidation, intermolecular transpeptidation, transamidation by added nucleophile Cavia porcellus
a
protein glutamine + alkylamine = protein N5-alkylglutamine + NH3 complex kinetic mechanism with substrate Z-Gln-Gly involving Gln hydrolysis, intramolecular transpeptidation, intermolecular transpeptidation, transamidation by added nucleophile Homo sapiens
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-methyl-casein + dansylcadaverine
-
 Cavia porcellus ?
-
 ?
N-methyl-casein + dansylcadaverine
-
 Homo sapiens ?
-
 ?
N-methyl-casein + O-methyl-Gly
-
 Cavia porcellus ?
-
 ?
N-methyl-casein + O-methyl-Gly
-
 Homo sapiens ?
-
 ?
Z-Gln-Gly + H2O
-
 Cavia porcellus ?
-
 ?
Z-Gln-Gly + H2O
-
 Homo sapiens ?
-
 ?
Z-Gln-Gly + O-methyl-Gly
-
 Cavia porcellus ?
-
 ?
Z-Gln-Gly + O-methyl-Gly
-
 Homo sapiens ?
-
 ?