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Literature summary for 2.3.2.12 extracted from
- A conserved base-pair between tRNA and 23 S rRNA in the peptidyl transferase center is important for peptide release (2006), J. Mol. Biol., 364, 1010-1020.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| C74G | 1.9fold inhibition in the rate of translocation of tRNA | Escherichia coli |
| G2252C | the rate of peptidyl transferase reaction is 100fold decreased | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-NTA agarose chromatography | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Met-tRNA + puromycin | - |
Escherichia coli | tRNA + Met-puromycin | - |
? |  |
| N-AcPhe-tRNA + puromycin | - |
Escherichia coli | tRNA + N-AcPhe-puromycin | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| peptidyl transferase | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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