Inhibitors | Comment | Organism | Structure |
---|---|---|---|
chloramphenicol | weak peptide bond formation inhibition only by ribosomes with A2451C, A2451U or A2451G, peptide bond formation inhibition by ribosomes with G2447A is essentially unimpaired | Geobacillus stearothermophilus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
ribosome | 50S subunit, wild type ribosomes, ribosomes with site-directed mutated residues: A2451, G2447 | Geobacillus stearothermophilus | 5840 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Geobacillus stearothermophilus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-AcMet-tRNA + puromycin | - |
Geobacillus stearothermophilus | tRNA + N-AcMet-puromycin | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
45 | - |
enzyme assay | Geobacillus stearothermophilus |