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Literature summary for 2.3.1.95 extracted from

  • Rimando, A.M.; Pan, Z.; Polashock, J.J.; Dayan, F.E.; Mizuno, C.S.; Snook, M.E.; Liu, C.J.; Baerson, S.R.
    In planta production of the highly potent resveratrol analogue pterostilbene via stilbene synthase and O-methyltransferase co-expression (2012), Plant Biotechnol. J., 10, 269-283.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
co-expression of AhSTS3 with Sorghum bicolor O-methyltransferase OMT3, EC 2.1.1.240, in Arabidopsis thaliana and Nicotiana tabacum using the CaMV 35S promoter and the Agrobacterium tumefaciens transfection method, quantitative realtime RT-PCR expression analysis in transgenic leaf samples, phenotypic analysis of pCRO1 transformants, overview. Subcloning in Escherichia coli. Binary vector construction Arachis hypogaea

Protein Variants

Protein Variants Comment Organism
additional information co-expression of stilbene synthase from Arachis hypogaea with the O-methyltransferase OMT3, EC 2.1.1.240, from Sorghum bicolor in Arabidopsis thaliana and Nicotiana tabacum, leading to production of pterostilbene, a 3,5-dimethylether derivative of resveratrol, but exhibiting significantly higher fungicidal activity in vitro and superior pharmacokinetic properties in vivo than resveratrol, overview. Accumulation of pterostilbene in both species Arachis hypogaea

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3 malonyl-CoA + 4-coumaroyl-CoA Arachis hypogaea
-
4 CoA + trans-resveratrol + 4 CO2
-
?

Organism

Organism UniProt Comment Textmining
Arachis hypogaea P51069
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3 malonyl-CoA + 4-coumaroyl-CoA
-
Arachis hypogaea 4 CoA + trans-resveratrol + 4 CO2
-
?

Synonyms

Synonyms Comment Organism
AhSTS3
-
Arachis hypogaea
stilbene synthase 3
-
Arachis hypogaea
stilbene synthase-type polyketide synthase enzyme
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Arachis hypogaea
STS-type PKS enzyme
-
Arachis hypogaea

General Information

General Information Comment Organism
evolution stilbene synthase 3 from Arachis hypogaea represents a type III PKS enzyme Arachis hypogaea