Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | growth of Acinetobacter baumannii or Escherichia coli harboring aac(6')-Ib in cultures containing 8 microg/ml amikacin is significantly inhibited by the addition of 2 microM Zn2+ in complex with the ionophore pyrithione | Acinetobacter baumannii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acinetobacter baumannii | - |
- |
- |
Acinetobacter baumannii 155 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + amikacin | - |
Acinetobacter baumannii | CoA + 6'-N-acetylamikacin | - |
? | |
acetyl-CoA + amikacin | - |
Acinetobacter baumannii 155 | CoA + 6'-N-acetylamikacin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AAC(6')-Ib | - |
Acinetobacter baumannii |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.015 | - |
pH not specified in the publication, temperature not specified in the publication | Acinetobacter baumannii | Zn2+ |