Any feedback?
Literature summary for 2.3.1.81 extracted from
- Stability of dactimicin to aminoglycoside-modifying enzymes produced by 341 bacterial clinical isolates (1989), Drugs Exp. Clin. Res., 15, 129-132.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + dactimicin | the percentage of dactimicin affinity relative to gentamicin C1a is very high (74.6%) only with AAC(3)-I, to the most other enzymes tested, in spite of the bifunctional AAC(6')/APH(2''), dactamicin is stable | Escherichia coli | CoA + N4-acetyldactamicin + N4,N6'-diacetyldactimicin | - |
? |  |
| acetyl-CoA + gentamicin C1a | - |
Escherichia coli | CoA + N3'-acetylgentamicin C1a | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
