Cloned (Comment) | Organism |
---|---|
cytogenetic analysis of skin fibroblast cell lines derived from enzyme-deficient mutant parent cell line and immortalized cell lines | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosomal membrane | transmembrane enzyme | Homo sapiens | 5765 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | enzyme deficiency causes mucopolysaccharidosis type IIIC | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partially, preparation of lysosomal membranes | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell culture | from primary skin fibroblasts, wild-type SF4528 and KD8, and MPS IIIC mutants thereof | Homo sapiens | - |
additional information | immortalization of cell lines, the cells retain the mucopolysaccharidosis type IIIC phenotype, overview | Homo sapiens | - |
skin fibroblast | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + phosphatidylethanolamine | - |
Homo sapiens | CoA + N-acetylphosphatidylethanolamine | - |
? | |
additional information | enzyme deficiency causes mucopolysaccharidosis type IIIC | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GNAT | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
acetyl-CoA | - |
Homo sapiens |