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Literature summary for 2.3.1.65 extracted from

  • Buch, C.; Hunt, M.C.; Alexson, S.E.; Hallberg, E.
    Localization of peroxisomal matrix proteins by photobleaching (2009), Biochem. Biophys. Res. Commun., 388, 355-359.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression of GFP-tagged enzyme in HeLa cells, which is exclusively located in the cytosol, high mobility of the GFP-fusion proteins in the cytosol and absence of peroxisomal escape Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information the cytosolic enzyme localization is due to a carboxyterminal non-consensus peroxisomal targeting signal, SQL, since mutation of the SQL to SKL results in BAAT being efficiently imported into peroxisomes Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol the cytosolic enzyme localization is due to a carboxyterminal non-consensus peroxisomal targeting signal, SQL, since mutation of the SQL to SKL results in BAAT being efficiently imported into peroxisomes Homo sapiens 5829
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peroxisome the cytosolic enzyme localization is due to a carboxyterminal non-consensus peroxisomal targeting signal, SQL, since mutation of the SQL to SKL results in BAAT being efficiently imported into peroxisomes Homo sapiens 5777
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
BAAT
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Homo sapiens
bile acid-CoA:amino acid N-acyltransferase
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Homo sapiens