Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.6 extracted from

  • Lian, W.; Gu, Y.; Pedersen, B.; Kukar, T.; Govindasamy, L.; Agbandje-McKenna, M.; Jin, S.; McKenna, R.; Wu, D.
    Crystallization and preliminary X-ray crystallographic studies on recombinant rat choline acetyltransferase (2004), Acta Crystallogr. Sect. D, 60, 374-375.
    View publication on PubMed
Search for more literature for 2.3.1.6

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli B834 Rattus norvegicus

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop vapor diffusion method Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Rattus norvegicus 16020
-
soluble 80-90% of total activity Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + choline Rattus norvegicus synthesis of the neurotransmitter acetylcholine acetylcholine + CoA
-
 r

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein phosphorylation enables membrane association Rattus norvegicus

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme using His-tag Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
neuron cholinergic neurons Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + choline
-
 Rattus norvegicus acetylcholine + CoA
-
 r
acetyl-CoA + choline synthesis of the neurotransmitter acetylcholine Rattus norvegicus acetylcholine + CoA
-
 r

Subunits

Subunits Comment Organism
monomer crystal structure analysis Rattus norvegicus