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Literature summary for 2.3.1.57 extracted from

  • Quick, D.M.; Wallace, H.M.
    Induction of spermidine/spermine N1-acetyltransferase in human breast carcinoma cells. A possible role for calcium (1993), Biochem. Pharmacol., 46, 969-974.
    View publication on PubMed
Search for more literature for 2.3.1.57

Activating Compound

Activating Compound Comment Organism Structure
additional information enzyme is induced by methylglyoxal bis(guanylhydrazone), potentiated by tetronasin or felodipine, tetronasin is also an active inducer, induction is related to the concentration of intracellular free calcium Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens rate-limiting enzyme in the degradation and interconversion of polyamines ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
T47D cell human breast carcinoma cell line Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + spermidine
-
 Homo sapiens CoA + N1-acetylspermidine
-
 ?
acetyl-CoA + spermine
-
 Homo sapiens CoA + N1-acetylspermine
-
 ?
additional information rate-limiting enzyme in the degradation and interconversion of polyamines Homo sapiens ?
-
 ?