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Literature summary for 2.3.1.51 extracted from

  • Yamashita, S.; Nakaya, N.; Miki, Y.; Numa, S.
    Separation of 1-acylglycerolphosphate acyltransferase and 1-acylglycerolphosphorylcholine acyltransferase of rat liver microsomes (1975), Proc. Natl. Acad. Sci. USA, 72, 600-603.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.51

General Stability

General Stability Organism
ethylene glycol, 20% v/v, stabilizes Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
Triton X-100 0.5 mM and above Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Rattus norvegicus
using solubilization with Triton X-100 and gel filtration, separation from EC 2.3.1.23 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1,2-diacyl-sn-glycerol 3-phosphate i.e. phosphatidic acid ?
arachidonoyl-CoA + 1-acyl-sn-glycerol 3-phosphate arachidonoyl-CoA is a poor substrate Rattus norvegicus CoA + 1-acyl-2-arachidonoyl-sn-glycerol 3-phosphate
-
 ?
lauroyl-CoA + 1-acyl-sn-glycerol 3-phosphate lauroyl-CoA is a poor substrate Rattus norvegicus CoA + 1-acyl-2-lauroyl-sn-glycerol 3-phosphate
-
 ?
linoleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate linoleoyl-CoA is a good substrate but is utilized less efficiently than oleoyl-CoA Rattus norvegicus CoA + 1-acyl-2-linoleoyl-sn-glycerol 3-phosphate
-
 ?
additional information the enzyme exhibits a considerable selectivity for monoenoic and dienoic fatty acyl-CoA thioesters Rattus norvegicus ?
-
 ?
myristoyl-CoA + 1-acyl-sn-glycerol 3-phosphate myristoyl-CoA is a poor substrate Rattus norvegicus CoA + 1-acyl-2-myristoyl-sn-glycerol 3-phosphate
-
 ?
oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate is the most effective acyl donor Rattus norvegicus CoA + 1-acyl-2-oleoyl-sn-glycerol 3-phosphate
-
 ?
palmitoleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate palmitoleoyl-CoA is a good substrate but is utilized less efficiently than oleoyl-CoA Rattus norvegicus CoA + 1-acyl-2-palmitoleoyl-sn-glycerol 3-phosphate
-
 ?
palmitoyl-CoA + 1-acyl-sn-glycerol 3-phosphate palmitoyl-CoA is a poor substrate Rattus norvegicus CoA + 1-acyl-2-palmitoyl-sn-glycerol 3-phosphate
-
 ?
stearoyl-CoA + 1-acyl-sn-glycerol 3-phosphate stearoyl-CoA is a poor substrate Rattus norvegicus CoA + 1-acyl-2-stearoyl-sn-glycerol 3-phosphate
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
43
-
 t1/2: 62 min Rattus norvegicus