Literature summary for 2.3.1.50 extracted from

Stoffel, W.; LeKim, D.; Sticht, G.
Biosynthesis of dihydrosphingosine in vitro (1968), Hoppe-Seyler's Z. Physiol. Chem., 349, 664-670.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endoplasmic reticulum	-	Wickerhamomyces ciferrii	5783	-
microsome	-	Rattus norvegicus	-	-
microsome	-	Wickerhamomyces ciferrii	-	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
palmitoyl-CoA + L-serine	Rattus norvegicus	-	CoA + 3-dehydro-D-sphinganine + CO2	-	ir
palmitoyl-CoA + L-serine	Wickerhamomyces ciferrii	-	CoA + 3-dehydro-D-sphinganine + CO2	-	ir

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-
Wickerhamomyces ciferrii	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
palmitoyl-CoA + L-serine	-	Rattus norvegicus	CoA + 3-dehydro-D-sphinganine + CO2	-	ir
palmitoyl-CoA + L-serine	-	Wickerhamomyces ciferrii	CoA + 3-dehydro-D-sphinganine + CO2	-	ir
palmitoyl-CoA + L-serine	-	Rattus norvegicus	CoA + 3-dehydro-D-sphinganine + CO2	i.e. 2-amino-1-hydroxyoctadecane-3-one, i.e. 3-oxo-dihydroxysphingosine	ir
palmitoyl-CoA + L-serine	-	Wickerhamomyces ciferrii	CoA + 3-dehydro-D-sphinganine + CO2	i.e. 2-amino-1-hydroxyoctadecane-3-one, i.e. 3-oxo-dihydroxysphingosine	ir

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Release 2023.1 (January 2023)