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Literature summary for 2.3.1.5 extracted from
- Reversible inhibition of the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 by S-nitrosothiols (2003), Biochem. Biophys. Res. Commun., 307, 1059-1065.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| S-nitroso-N-acetyl-DL-penicillamine | reversible inactivation due to direct atteck of the highly reactive cysteine residue in the enzyme active site on the sulfur of S-nitrosothiols to form a mixed disulfide between these NO-derived oxidants and NAT1 | Homo sapiens |  |
| S-nitrosoglutathione | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| p-nitrophenylacetate + p-aminosalicylic acid | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| arylamine N-acetyltransferase 1 | - |
Homo sapiens |
| NAT1 | - |
Homo sapiens |
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