Cloned (Comment) | Organism |
---|---|
expression of Esa1 gene in Escherichia coli | Saccharomyces cerevisiae |
Protein Variants | Comment | Organism |
---|---|---|
additional information | temperature sensitive Esa1 mutant strain shows reduced activity in vitro and needs histone H4 acetylated at Lys5 as substrate in vivo | Saccharomyces cerevisiae |
additional information | diverse Esa1 gene mutant strains, overview | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + histone | Saccharomyces cerevisiae | Esa1 protein is involved in cell cycle regulation | CoA + acetylhistone | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
Esa1 gene | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + histone | - |
Saccharomyces cerevisiae | CoA + acetylhistone | - |
? | |
acetyl-CoA + histone | Esa1 protein is involved in cell cycle regulation | Saccharomyces cerevisiae | CoA + acetylhistone | - |
? | |
acetyl-CoA + histone H2A | - |
Saccharomyces cerevisiae | CoA + acetylhistone H2A | - |
? | |
acetyl-CoA + histone H3 | - |
Saccharomyces cerevisiae | CoA + acetylhistone H3 | - |
? | |
acetyl-CoA + histone H4 | histone H4 is the preferred substrate | Saccharomyces cerevisiae | CoA + acetylhistone H4 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HAT | - |
Saccharomyces cerevisiae |
More | enzymes with histone acetyltransferase and transcription cofactor activity belong to the MYST protein family | Saccharomyces cerevisiae |