Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.43 extracted from

  • Dullaart, R.P.; Perton, F.; Sluiter, W.J.; de Vries, R.; van Tol, A.
    Plasma lecithin:cholesterol acyltransferase activity is elevated in metabolic syndrome and is an independent marker of increased carotid artery intima media thickness (2008), J. Clin. Endocrinol. Metab., 93, 4860-4866.
    View publication on PubMed

Application

Application Comment Organism
medicine carotid artery intima media thickness (IMT) is greater and plasma LCAT activity is higher in subjects with metabolic syndromes compared to control. Similar increases in IMT and LCAT are found in MetS subjects without type 2 diabetes mellitus. In addition, plasma LCAT activity is independently and positively related to insulin resistance, plasma triglycerides, non-HDL cholesterol and HDL cholesterol. LCAT activity may be a marker of subclinical atherosclerosis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
LCAT
-
Homo sapiens
lecithin-cholesterol acyltransferase
-
Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Homo sapiens