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Literature summary for 2.3.1.43 extracted from

  • Ayyobi, A.F.; Lacko, A.G.; Murray, K.; Nair, M.; Li, M.; Molhuizen, H.O.F.; Pritchard, P.H.
    Biochemical and compositional analyses of recombinant lecithin:cholesterol acyltransferase (LCAT) obtained from a hepatic source (2000), Biochim. Biophys. Acta, 1484, 1-13.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
apolipoprotein A-I activates recombinant enzymes Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expression in baby hamster kidney cells Homo sapiens
expression in hepatic Mc-7777 cells Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.57
-
cholesterol recombinant enzyme expressed in baby hamster kidney cells Homo sapiens
0.83
-
cholesterol recombinant enzyme expressed in hepatic Mc-7777 cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein recombinant enzyme expressed in hepatic Mc-7777 cells has biantennary structure oligosaccharide moieties Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
purification of recombinant enzymes Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphatidylcholine + sterol
-
Homo sapiens 1-acylglycerophosphocholine + sterol ester
-
?

Subunits

Subunits Comment Organism
?
-
Homo sapiens