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Literature summary for 2.3.1.43 extracted from
- Purification of human plasma lecithin:cholesterol acyltransferase and its activation by metal ions (1980), Can. J. Biochem., 58, 539-541.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Co2+ | stimulates phospholipase reaction and cholesterol esterification, EDTA suppresses stimulation | Homo sapiens |  |
| Cu2+ | stimulates phospholipase reaction and cholesterol esterification, EDTA suppresses stimulation | Homo sapiens | |
| Ni2+ | stimulates phospholipase reaction and cholesterol esterification, EDTA suppresses stimulation | Homo sapiens | |
| Zn2+ | stimulates phospholipase reaction and cholesterol esterification, EDTA suppresses stimulation | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| HDL-Sepharose, agglutinin-Sepharose chromatography and polyacrylamide electrophoresis | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| plasma | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Homo sapiens |
| 0.08 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phosphatidylcholine + sterol | - |
Homo sapiens | 1-acylglycerophosphocholine + sterol ester | - |
r | |
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Release 2023.1 (January 2023)
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