Activating Compound | Comment | Organism | Structure |
---|---|---|---|
albumin | phospholipase activity is dependent on | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,5'-dithiobis(2-nitrobenzoic acid) | - |
Homo sapiens | |
Ag+ | - |
Homo sapiens | |
lysolecithin | inhibition of LCAT activity | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | Ca2+-independent | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Sephadex G-100, hydroxyapatite and affinity column chromatography | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.34 | - |
at 37°C in cholesterol-lecithin vesicles | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | phospholipase activity | Homo sapiens | ? | - |
? | |
phosphatidylcholine + sterol | predominant but incomplete specificity for reaction at position 2 of mixed lecithins | Homo sapiens | 1-acylglycerophosphocholine + sterol ester | - |
r |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | 8 | lecithin-cholesterol acyltransferase activity | Homo sapiens |
8 | - |
phospholipase activity | Homo sapiens |