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Literature summary for 2.3.1.43 extracted from
- Purification and partial characterization of a bacterial phospholipid: cholesterol acyltransferase (1982), J. Biol. Chem., 257, 3320-3325.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| albumin | stimulates | Aeromonas salmonicida | |
| apolipoprotein A-I | - |
Aeromonas salmonicida |
General Stability
| General Stability | Organism |
|---|---|
| unaffected by repeated freezing and thawing | Aeromonas salmonicida |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no divalent cation requirement | Aeromonas salmonicida |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 23600 | - |
x * 23600, SDS-PAGE | Aeromonas salmonicida |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aeromonas salmonicida | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| extraction from cell membranes with Tween 20, purification by Sephadex G-100 and DEAE-Sepharose columns | Aeromonas salmonicida |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 137 | - |
in cholesterol-lecithin vesicles | Aeromonas salmonicida |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | bacterial enzyme is not specific for phosphatidylcholine, it can use human erythrocyte membrane substrates, 2-positional specificity as acyltransferase | Aeromonas salmonicida | ? | - |
? |  |
| additional information | phospholipase A2 activity | Aeromonas salmonicida | ? | - |
? | |
| phosphatidylcholine + sterol | - |
Aeromonas salmonicida | 1-acylglycerophosphocholine + sterol ester | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 23600, SDS-PAGE | Aeromonas salmonicida |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 9 | activity is independent of pH in this range | Aeromonas salmonicida |
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