Literature summary for 2.3.1.37 extracted from

Buzaleh, A.M.; Moran-Jimenez, M.J.; Garcia-Bravo, M.; Sampedro, A.; Batlle, A.M.; Enriquez de Salamanca, R.; Fontanellas, A.
Induction of hepatic aminolevulinate acid synthetase activity by isoflurane in a genetic model for erythropoietic protoporphyria (2009), Cell. Mol. Biol., 55, 38-44.

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Application

Application	Comment	Organism
medicine	in mouse model of erythropoietic protoporphyria, isoflurane induces 5-aminolevulinate synthase activity and increases excretion of porphyrin precursors. Mice homozygotically lacking ferrochelatase activity and receiving anaestesia show enhanced 5-aminolevulinate synthase and Cyp2E1 activities in the liver and increased urinary excretion of porphyrin precursors	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Expression

Organism	Comment	Expression
Mus musculus	in mouse model of erythropoietic protoporphyria, isoflurane induces 5-aminolevulinate synthase activity and increases excretion of porphyrin precursors	up

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Release 2023.1 (January 2023)