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Literature summary for 2.3.1.37 extracted from

  • Simpson, D.M.; Beattie, D.S.
    Purification of a specific activator of solubilized delta-aminolevulinic acid synthetase from rat liver mitochondria (1980), J. Biol. Chem., 255, 1630-1634.
    View publication on PubMed
Search for more literature for 2.3.1.37

Activating Compound

Activating Compound Comment Organism Structure
Activator protein from rat liver mitochondria possibly activates by formation of high molecular weight aggregates of delta-aminolevulinic acid synthetase Rattus norvegicus
native activator protein purified from hepatic extract Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Rattus norvegicus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
54000
-
 2 * 54000, SDS-PAGE Rattus norvegicus
58000
-
 monomer, gel filtration Rattus norvegicus
118000
-
 dimer, gel filtration Rattus norvegicus
218000
-
 tetramer of enzyme and native activator protein, gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
succinyl-CoA + glycine
-
 Rattus norvegicus 5-aminolevulinate + CoA + CO2
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 54000, SDS-PAGE Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
additional information
-
 pI: 7.5 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Rattus norvegicus