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Literature summary for 2.3.1.37 extracted from
- Control of 5-aminolevulinic acid synthetase activity in phototrophic facultative bacteria. Purification and some properties of the enzyme from Rhodospirillum rubrum (1981), Biochimie, 63, 439-444.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| phosphate | enzyme is maximally active in presence of 0.005 mM phosphate | Rhodospirillum rubrum |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Cu2+ | isoenzyme a | Rhodospirillum rubrum | |
| hemin | - |
Rhodospirillum rubrum | |
| Hg2+ | isoenzyme a | Rhodospirillum rubrum | |
| p-chloromercuribenzoate | isoenzyme a | Rhodospirillum rubrum | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 65000 | 70000 | - |
Rhodospirillum rubrum |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rhodospirillum rubrum | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| 2 isoenzymes: A and B | Rhodospirillum rubrum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinyl-CoA + glycine | - |
Rhodospirillum rubrum | 5-aminolevulinate + CoA + CO2 | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.1 | 7.5 | isoenzyme A | Rhodospirillum rubrum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Rhodospirillum rubrum | |
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