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Literature summary for 2.3.1.31 extracted from

  • Nagai, S.; Flavin, M.
    Acetylhomoserine. An intermediate in the fungal biosynthesis of methionine (1967), J. Biol. Chem., 242, 3884-3895.
    View publication on PubMed
Search for more literature for 2.3.1.31

Protein Variants

Protein Variants Comment Organism
additional information methionine deficient strains do not perform the L-homoserine/O-acetyl-L-homoserine exchange reaction Neurospora sp.

Inhibitors

Inhibitors Comment Organism Structure
acetylcarnitine
-
 Neurospora sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + L-homoserine Neurospora sp.
-
 CoA + O-acetyl-L-homoserine intermediate in methionine biosynthesis ?

Organism

Organism UniProt Comment Textmining
Neurospora sp.
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Neurospora sp.

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Neurospora sp.
0.0036
-
-
 Neurospora sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + L-homoserine
-
 Neurospora sp. CoA + O-acetyl-L-homoserine intermediate in methionine biosynthesis ?
acetyl-CoA + L-homoserine acetyl imidazole cannot replace acetyl-CoA Neurospora sp. CoA + O-acetyl-L-homoserine
-
 ?
acetyl-CoA + L-homoserine acetyl phosphate, acetyl carnitine, acetyl-[acyl-carrier-protein] from E. coli Neurospora sp. CoA + O-acetyl-L-homoserine
-
 ?
additional information catalyzes reversible L-homoserine/O-acetyl-L-homoserine exchange in the absence of acetyl-CoA Neurospora sp. ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Neurospora sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.3 7.5 assay at Neurospora sp.