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Literature summary for 2.3.1.26 extracted from

  • Locke, J.; Wasan, K.; Nelson, C.; Guns, E.; Leon, C.
    Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:cholesterol acyltransferase (ACAT) (2008), Prostate, 68, 20-33.
    View publication on PubMed
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
LNCaP cell
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 Homo sapiens
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PC-3 cell
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 Homo sapiens
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Expression

Organism Comment Expression
Homo sapiens no effect from androgen treatment on ACAT1 protein expression in LNCaP cells nor from treatment on ACAT2 expression in PC-3 cells additional information
Homo sapiens ACAT2 expression is induced upon androgen agonist R1881 treatment of LNCaP cells. Increase in the in vitro ACAT1 activity in PC-3 cells treated with androgen up
Homo sapiens in PC-3 cells treated with androgen agonist R1881, ACAT1 protein expression and cholesterol ester levels are decreased up