Literature summary for 2.3.1.26 extracted from

Song, M.C.; Yang, H.J.; Jeong, T.S.; Kim, K.T.; Baek, N.I.
Heterocyclic compounds from Chrysanthemum coronarium L. and their inhibitory activity on hACAT-1, hACAT-2, and LDL-oxidation (2008), Arch. Pharm. Res., 31, 573-578.

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Inhibitors

Inhibitors	Comment	Organism	Structure
5,5'-dibutoxy-2,2'-bifuran	-	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
acyl-CoA + cholesterol	Homo sapiens	-	CoA + cholesterol ester	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acyl-CoA + cholesterol	-	Homo sapiens	CoA + cholesterol ester	-	?

Synonyms

Synonyms	Comment	Organism
acyl-CoA:cholesterol acyltransferase	-	Homo sapiens
hACAT-1	-	Homo sapiens
hACAT-2	-	Homo sapiens

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.16	-	-	Homo sapiens	5,5'-dibutoxy-2,2'-bifuran
0.19	-	-	Homo sapiens	5,5'-dibutoxy-2,2'-bifuran

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Release 2023.1 (January 2023)