Activating Compound | Comment | Organism | Structure |
---|---|---|---|
albumin | - |
Rattus norvegicus | |
albumin | stimulates | Oryctolagus cuniculus | |
cholesterol | exogenous, not stimulatory | Oryctolagus cuniculus | |
cholesterol | exogenous, 25% increase of adrenal microsome activity and 2fold increase of activity in liver | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bovine serum albumin | inhibits at high concentrations | Oryctolagus cuniculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | submicrosomal distribution | Rattus norvegicus | - |
- |
microsome | submicrosomal distribution | Oryctolagus cuniculus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Rattus norvegicus | - |
adrenal gland | - |
Oryctolagus cuniculus | - |
aorta | - |
Rattus norvegicus | - |
aorta | atheroschlerotic tissue | Oryctolagus cuniculus | - |
liver | - |
Rattus norvegicus | - |
liver | - |
Oryctolagus cuniculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Rattus norvegicus |
additional information | - |
enhancement of activity following 8-11 weeks of cholesterol feeding | Oryctolagus cuniculus |
0.0001042 | - |
aortic microsomal preparation | Oryctolagus cuniculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + cholesterol | - |
Rattus norvegicus | CoA + cholesterol ester | - |
? | |
acyl-CoA + cholesterol | - |
Oryctolagus cuniculus | CoA + cholesterol ester | - |
? | |
oleoyl-CoA + cholesterol | - |
Rattus norvegicus | CoA + cholesteryl oleate | - |
? | |
oleoyl-CoA + cholesterol | - |
Oryctolagus cuniculus | CoA + cholesteryl oleate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
37 | - |
assay at | Oryctolagus cuniculus |