Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.24 extracted from

  • Xu, Z.; Zhou, J.; McCoy, D.M.; Mallampalli, R.K.
    LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia (2005), J. Lipid Res., 46, 1229-1238.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
MLE cells transiently transfected with His-tagged LASS5 plasmid Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + sphingosine Mus musculus LASS5 is the major ceramide synthase gene product involved in sphingolipid production that may also regulate PtdCho metabolism in pulmonary epithelia ?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus Q9D6K9
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
lung LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + sphingosine LASS5 is the major ceramide synthase gene product involved in sphingolipid production that may also regulate PtdCho metabolism in pulmonary epithelia Mus musculus ?
-
?
palmitoyl-CoA + sphingosine
-
Mus musculus CoA + N-palmitoylsphingosine
-
?

Synonyms

Synonyms Comment Organism
LAG1 longevity assurance homolog 5
-
Mus musculus
LASS5
-
Mus musculus
longevity assurance homolog 5
-
Mus musculus
TRAM homolog 4
-
Mus musculus
translocating chain-associating membrane protein homolog 4
-
Mus musculus