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Literature summary for 2.3.1.23 extracted from
- Lysophospholipid acyltransferases: novel potential regulators of the inflammatory response and target for new drug discovery (2008), Pharmacol. Ther., 119, 104-114.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-[5-(thiophen-3-yl)pyridin-3-yl]ethanol | non-competitive | Homo sapiens |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.027 | - |
lysophosphatidylcholine | - |
Bos taurus | |
| 0.1 | - |
oleoyl-CoA | - |
Bos taurus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
| microsome | - |
Bos taurus | - |
- |
| microsome | - |
Mus musculus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Homo sapiens | Q8NF37 | - |
- |
| Mus musculus | Q3TFD2 | - |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
| lung | - |
Rattus norvegicus | - |
| lung | - |
Mus musculus | - |
| monocyte | - |
Homo sapiens | - |
| neutrophil | - |
Homo sapiens | - |
| retina | outer rod segment | Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lysophosphatidylcholine + acyl-CoA | - |
Rattus norvegicus | phosphatidylcholine + CoA | - |
? | |
| lysophosphatidylcholine + acyl-CoA | - |
Mus musculus | phosphatidylcholine + CoA | - |
? | |
| lysophosphatidylcholine + acyl-CoA | - |
Homo sapiens | phosphatidylcholine + CoA | - |
? | |
| lysophosphatidylcholine + oleoyl-CoA | - |
Bos taurus | phosphatidylcholine + CoA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 1-acylglycerophosphocholine acyltransferase | - |
Rattus norvegicus |
| 1-acylglycerophosphocholine acyltransferase | - |
Bos taurus |
| 1-acylglycerophosphocholine acyltransferase | - |
Mus musculus |
| 1-acylglycerophosphocholine acyltransferase | - |
Homo sapiens |
| LPCAT | - |
Rattus norvegicus |
| LPCAT | - |
Bos taurus |
| LPCAT | - |
Mus musculus |
| LPCAT | - |
Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
- |
Bos taurus |
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