Literature summary for 2.3.1.226 extracted from

Hamed, R.B.; Gomez-Castellanos, J.R.; Froese, D.S.; Krysztofinska, E.; Yue, W.W.; Schofield, C.J.
Use of methylmalonyl-CoA epimerase in enhancing crotonase stereoselectivity (2015), ChemBioChem, 17, 1-7.

Search for more literature for 2.3.1.226

Application

Application	Comment	Organism
synthesis	coupling of methylmalonyl-CoA epimerase, crotonyl-CoA carboxylase reductase and carboxymethylproline synthase mutants in a three-enzyme one-pot sequential synthesis of functionalised C-5 carboxyalkylprolines starting from crotonyl-CoA and carbon dioxide	Pectobacterium carotovorum

Protein Variants

Protein Variants	Comment	Organism
M108V	mutant is able to convert (2S)-methylmalonyl-CoA/L-glutamate semialdehyde/5-hydroxyproline/pyrroline-5-carboxylate to (6R)-6-methyl-(2S,5S)-5-carboxymethylproline	Pectobacterium carotovorum
W79F	mutant is able to convert (2S)-ethylmalonyl-CoA/L-glutamate semialdehyde/5-hydroxyproline/pyrroline-5-carboxylate to (6R)-6-ethyl-(2S,5S)-5-carboxymethylproline	Pectobacterium carotovorum

Organism

Organism	UniProt	Comment	Textmining
Pectobacterium carotovorum	Q9XB60	subsp. carotovorum	-

Synonyms

Synonyms	Comment	Organism
CarB	-	Pectobacterium carotovorum

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Release 2023.1 (January 2023)