Literature summary for 2.3.1.225 extracted from

Zhang, Y.L.; Li, E.; Feng, Q.N.; Zhao, X.Y.; Ge, F.R.; Zhang, Y.; Li, S.
Protein palmitoylation is critical for the polar growth of root hairs in Arabidopsis (2015), BMC Plant Biol., 15, 50.

Search for more literature for 2.3.1.225

Inhibitors

Inhibitors	Comment	Organism	Structure
2-Bromopalmitate	specific inhibitor for protein palmitoylation. Treatment compromises root hair elongation and polarity; specific inhibitor for protein palmitoylation. Treatment compromises root hair elongation and polarity	Arabidopsis thaliana

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
Golgi apparatus	-	Arabidopsis thaliana	5794	-
tonoplast	-	Arabidopsis thaliana	-	-

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	Q52T38	-	-
Arabidopsis thaliana	Q7XA86	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
root hair	-	Arabidopsis thaliana	-

Synonyms

Synonyms	Comment	Organism
PAT10	-	Arabidopsis thaliana
PAT24	-	Arabidopsis thaliana

General Information

General Information	Comment	Organism
physiological function	isoform PAT10 plays a secondary role in root hair growth. Treatment with palmitoylation-specific inhibitor 2-bromopalmitate compromises root hair elongation and polarity and impairs the dynamic polymerization of actin microfilaments, the asymmetric plasma membrane localization of phosphatidylinositol (4,5)-bisphosphate, the dynamic distribution of RabA4b-positive post-Golgi secretion, and endocytic trafficking in root hairs	Arabidopsis thaliana
physiological function	protein palmitoylation, contributed primarily by the Golgi-localized isoform TIP1 and secondarily by protein S-acyl transferases from other endomembrane compartments, plays a key role in the polar growth of root hairs. Treatment with specific inhibitor 2-bromopalmitate compromises root hair elongation and polarity and impairs the dynamic polymerization of actin microfilaments, the asymmetric plasma membrane localization of phosphatidylinositol (4,5)-bisphosphate, the dynamic distribution of RabA4b-positive post-Golgi secretion, and endocytic trafficking in root hairs	Arabidopsis thaliana

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Release 2023.1 (January 2023)