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Literature summary for 2.3.1.22 extracted from
- Solubilization and partial purification of neonatally expressed rat hepatic microsomal monoacylglycerol acyltransferase (1993), Arch. Biochem. Biophys., 300, 663-669.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Phospholipid | phosphatidylcholine/phosphatidylserine at 0.025 mg/ml stimulates 80% | Rattus norvegicus |  |
| sn-1,2-dioleoylglycerol | 0.3 mM, stimulates 44% | Rattus norvegicus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| beta-octylglucoside | 2.5% | Rattus norvegicus | |
| CHAPS | 1.5% | Rattus norvegicus | |
| taurocholate | 2% | Rattus norvegicus | |
| Triton X-100 | no inhibition | Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0065 | - |
palmitoyl-CoA | - |
Rattus norvegicus | |
| 0.0071 | - |
sn-2-monolinolenoylglycerol | - |
Rattus norvegicus | |
| 0.011 | - |
sn-2-monolinoleoylglycerol | - |
Rattus norvegicus | |
| 0.021 | - |
sn-2-monooleoylglycerol | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | neonatal | Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 1.219 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-CoA + sn-2-monolinolenoylglycerol | in preference to sn-2-monooleoylglycerol | Rattus norvegicus | CoA + 1-acyl-2-linolenoylglycerol | - |
? | |
| acyl-CoA + sn-2-monolinoleoylglycerol | in preference to sn-2-monooleoylglycerol | Rattus norvegicus | CoA + 1-acyl-2-linoleoylglycerol | - |
? | |
| fatty acyl-CoA + sn-2-monoacylglycerol | - |
Rattus norvegicus | CoA + 1,2-diacylglycerol | - |
? | |
| palmitoyl-CoA + sn-2-monooleoylglycerol | - |
Rattus norvegicus | CoA + 1(3)-palmitoyl-2-oleoylglycerol | - |
? | |
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