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Literature summary for 2.3.1.21 extracted from
- Modulation of the hepatic malonyl-CoA-carnitine palmitoyltransferase 1A partnership creates a metabolic switch allowing oxidation of de novo fatty acids (2009), Biochem. J., 420, 429-438.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| adenovirus-mediated (over)expression in cultured fed rat hepatocyte | Rattus norvegicus |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| M593S | malonyl-CoA-insensitive mutant | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| malonyl-CoA | - |
Rattus norvegicus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-carnitine + palmitoyl-CoA | - |
Rattus norvegicus | L-palmitoylcarnitine + CoA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| carnitine palmitoyltransferase 1 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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