KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | the apparent KM-value in liver increases from birth to 3 weeks and then decreases and remains constant after 6 weeks of age. The highest Km-value is in 3-week old dogs and is about 50% greater than in older dogs. The apparent Km-value for carnitine measured in muscle is relatively constant in dogs of all ages tested. The apparent KM-for carnitine is 27% lower in muscle than in liver. Carnitine may have an important role in the regulation of fatty acid oxidation and incrrased dietary carnitine may improve fatty acid oxidative capacity in developing dogs | Canis lupus familiaris |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Canis lupus familiaris | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | activity is low at birth, increases by 100% during the suckling period and declines after weaning to adult levels | Canis lupus familiaris | - |
skeletal muscle | activity continues to increase with age, reaching adult levels after 9 weeks. Concentration in adult is 10fold the apparent Km-value for carnitine | Canis lupus familiaris | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
palmitoyl-CoA + L-carnitine | - |
Canis lupus familiaris | CoA + L-palmitoylcarnitine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CPT | - |
Canis lupus familiaris |