Cloned (Comment) | Organism |
---|---|
overexpression of M-CPT I in Pichia pastoris, containing about 24 copies of the expression vector | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
malonyl-CoA | CPT II not inhibited; CPT I, native and reconstituted in phospholipid micelles | Homo sapiens | |
Triton X-100 | recombinant CPT I, complete inactivation at 5%, at least partly reversible | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + L-carnitine | Homo sapiens | - |
CoA + L-acylcarnitine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
M-CPT I | - |
Purification (Comment) | Organism |
---|---|
recombinant M-CPT I from Pichia pastoris | Homo sapiens |
Renatured (Comment) | Organism |
---|---|
reconstitution of detergent-inactivated recombinant M-CPT I, purified from Pichia pastoris, by removal of detergents in presence of phospholipids | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | M-CPT I | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + L-carnitine | - |
Homo sapiens | CoA + L-acylcarnitine | - |
? |