General Stability | Organism |
---|---|
fractionation causes rapid loss of CPTo activity, CPTi is relatively stable | Rattus norvegicus |
solubilization causes rapid loss of CPTo activity, CPTi is relatively stable | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
etomoxir-CoA | CPTo | Rattus norvegicus | |
malonyl-CoA | CPTo | Rattus norvegicus | |
tetradecylglycidyl-CoA | CPTo | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial inner membrane | enzyme from outer and from inner membrane have different properties | Rattus norvegicus | 5743 | - |
mitochondrial outer membrane | enzyme from outer and from inner membrane have different properties | Rattus norvegicus | 5741 | - |
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + L-carnitine | Rattus norvegicus | - |
CoA + L-acylcarnitine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + L-carnitine | - |
Rattus norvegicus | CoA + L-acylcarnitine | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | CPTo and CPTi are distinct proteins, 90000 MW subunit of liver and 86000 MW subunit of muscle constitutes a component of their respective CPTo system, the 66000 MW subunit of CPTi does not constitute a part of the CPTo system | Rattus norvegicus |