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Literature summary for 2.3.1.21 extracted from
- Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver (1983), J. Biochem., 94, 529-542.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| di(2-ethyl-hexyl)phtalate | - |
Rattus norvegicus |  |
General Stability
| General Stability | Organism |
|---|---|
| quite stable at all steps of purification | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-bromopalmitoyl-CoA | no inhibition | Rattus norvegicus | |
| malonyl-CoA | - |
Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Rattus norvegicus | 16020 | - |
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
| nucleus | - |
Rattus norvegicus | 5634 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 69200 | - |
x * 69200, SDS-PAGE | Rattus norvegicus |
| 280000 | 320000 | gel filtration | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-CoA + L-carnitine | Rattus norvegicus | - |
CoA + L-acylcarnitine | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 29.6 | - |
purified enzyme | Rattus norvegicus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, several months | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-CoA + L-carnitine | - |
Rattus norvegicus | CoA + L-acylcarnitine | - |
r | |
| acyl-CoA + L-carnitine | substrate specificity | Rattus norvegicus | CoA + L-acylcarnitine | - |
r | |
| palmitoyl-CoA + L-carnitine | - |
Rattus norvegicus | CoA + L-palmitoylcarnitine | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 69200, SDS-PAGE | Rattus norvegicus |
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