Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
additional information | junctions between cortical parenchyma cells | Malus domestica | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
43000 | - |
x * 43000, BIS3, SDS-PAGE | Malus domestica |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
malonyl-CoA + 2-hydroxybenzoyl-CoA | Malus domestica | - |
2 CoA + 4-hydroxycoumarin + CO2 | - |
? | |
malonyl-CoA + 2-hydroxybenzoyl-CoA | Sorbus aucuparia | - |
2 CoA + 4-hydroxycoumarin + CO2 | - |
? | |
additional information | Malus domestica | for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule | ? | - |
? | |
additional information | Sorbus aucuparia | for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Malus domestica | - |
cv. Holsteiner Cox | - |
Sorbus aucuparia | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bark | BIS3, parenchyma of the bark | Malus domestica | - |
cell culture | elicitor-treated cell cultures | Sorbus aucuparia | - |
leaf | BIS2 | Malus domestica | - |
shoot | - |
Malus domestica | - |
stem | - |
Malus domestica | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
malonyl-CoA + 2-hydroxybenzoyl-CoA | - |
Malus domestica | 2 CoA + 4-hydroxycoumarin + CO2 | - |
? | |
malonyl-CoA + 2-hydroxybenzoyl-CoA | - |
Sorbus aucuparia | 2 CoA + 4-hydroxycoumarin + CO2 | - |
? | |
additional information | for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule | Malus domestica | ? | - |
? | |
additional information | for the bifunctional BIS, the preferred starter substrates are benzoyl-CoA and salicoyl-CoA, leading to the formation of 3,5-dihydroxybiphenyl and 4-hydroxycoumarin, EC 2.3.1.177 and 2.3.1.208, respectively, in the presence of malonyl-CoA as extender molecule | Sorbus aucuparia | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 43000, BIS3, SDS-PAGE | Malus domestica |
Synonyms | Comment | Organism |
---|---|---|
biphenyl synthase | - |
Malus domestica |
biphenyl synthase | - |
Sorbus aucuparia |
BIS | - |
Malus domestica |
BIS | - |
Sorbus aucuparia |
BIS3 | - |
Malus domestica |
Organism | Comment | Expression |
---|---|---|
Malus domestica | BIS2 and BIS3 are not induced by phytoalexins, e.g. Erwinia amylovora, applicated to the shoot | additional information |
Sorbus aucuparia | BIS is induced by elicitors in cell culture | up |
General Information | Comment | Organism |
---|---|---|
evolution | biphenyl synthase is a type III polyketide synthase | Malus domestica |
evolution | biphenyl synthase is a type III polyketide synthase | Sorbus aucuparia |
physiological function | BIS3 appears to catalyze the formation of phytoalexins in the transition zone, while BIS2 does not | Malus domestica |