Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.20 extracted from

  • Chung, M.Y.; Rho, M.C.; Ko, J.S.; Ryu, S.Y.; Jeune, K.H.; Kim, K.; Lee, H.S.; Kim, Y.K.
    In vitro inhibition of diacylglycerol acyltransferase by prenylflavonoids from Sophora flavescens (2004), Planta Med., 70, 258-260.
    View publication on PubMed
Search for more literature for 2.3.1.20

Inhibitors

Inhibitors Comment Organism Structure
(2R,3R)-2-(2,4-Dihydroxy-phenyl)-3,7-dihydroxy-8-((R)-5-hydroxy-2-isopropenyl-5-methyl-hexyl)-5-methoxy-chroman-4-one i.e. kushenol H, prenylflavonoid from Sophora flavescens, 50% inhibition at 0.142 mM Rattus norvegicus
(2R,3S)-2-(2,4-Dihydroxy-phenyl)-3,7-dihydroxy-8-((R)-5-hydroxy-2-isopropenyl-5-methyl-hexyl)-5-methoxy-chroman-4-one i.e. kushenol K, prenylflavonoid from Sophora flavescens, 50% inhibition at 0.250 mM Rattus norvegicus
1-[2,4-dihydroxy-3-(2-isopropenyl-5-methyl-hex-4-enyl)-6-methoxy-phenyl]-3-(2,4-dihydroxy-phenyl)-propenone i.e. kuraridin, prenylflavonoid from Sophora flavescens, 50% inhibition at 0.099 mM Rattus norvegicus
2-(2,4-dihydroxy-phenyl)-7-hydroxy-8-(2-isopropenyl-5-methyl-hex-4-enyl)-5-methoxy-chroman-4-one i.e. kurarinone, prenylflavonoid from Sophora flavescens, 50% inhibition at 0.0109 mM Rattus norvegicus
2-(2,4-dihydroxy-phenyl)-7-hydroxy-8-[2-(3-hydroxy-3-methyl-butyl)-3-methyl-but-3-enyl]-5-methoxy-chroman-4-one i.e. kurarinol, prenylflavonoid from Sophora flavescens, 50% inhibition at 0.0086 mM Rattus norvegicus
additional information not inhibitory: hesperetin, naringenin, quercetin, kaempferol up to 0.8 mM Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-