Literature summary for 2.3.1.198 extracted from

Chen, X.; Chen, G.; Truksa, M.; Snyder, C.L.; Shah, S.; Weselake, R.J.
Glycerol-3-phosphate acyltransferase 4 is essential for the normal development of reproductive organs and the embryo in Brassica napus (2014), J. Exp. Bot., 65, 4201-4215.

Search for more literature for 2.3.1.198

Organism

Organism	UniProt	Comment	Textmining
Brassica napus	H9XTI6 and H9XTI4 and H9XTI5	H9XTI6, i.e. isoform Gpat4-A1, H9XTI4 i.e. isoform Gpat4-C1, H9XTI5, i.e. isoform Gpat4-C2	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	all three Gpat4 isoforms exhibit sn-2 acyltransferase and phosphatase activities with dicarboxylic acid-CoA as acyl donor. When non-substituted acyl-CoA is used as acyl donor, the rate of acylation is considerably lower and phosphatase activity is not manifested	Brassica napus	?	-	?
sn-glycerol 3-phosphate + 15-carboxypentadecanoyl-CoA	-	Brassica napus	CoA + 2-(15-carboxypentadecanoyl)-sn-glycerol 3-phosphate	reaction mainly occurs in sn-2 position. Intrinsic phosphatase activity of the enzymes finally leads to formation of 2-(15-carboxypentadecanoyl)-sn-glycerol	?
sn-glycerol 3-phosphate + palmitoyl-CoA	-	Brassica napus	CoA + 2-palmitoyl-sn-glycerol 3-phosphate	phosphatase activity of the enzymes does not act on non-substituted acyl residues	?

Synonyms

Synonyms	Comment	Organism
GPAT4	-	Brassica napus

General Information

General Information	Comment	Organism
physiological function	RNAi-mediated down-regulation of all Gpat4 homologues causes abnormal development of several reproductive organs and reduced seed set. Both pollen grains and developing embryo sacs of the downregulated Gpat4 lines are affected. The gpat4 mature embryos show decreased cutin content and altered monomer composition. The defective embryo development affects the oil body morphology, oil content, and fatty acid composition in Gpat4-lacking seeds	Brassica napus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)