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Literature summary for 2.3.1.191 extracted from

  • Yeom, D.H.; Kim, S.K.; Lee, M.N.; Lee, J.H.
    Pleiotropic effects of acyltransferases on various virulence-related phenotypes of Pseudomonas aeruginosa (2013), Genes Cells, 18, 682-693.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa Q9HXY6
-
-

Synonyms

Synonyms Comment Organism
LpxD
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Pseudomonas aeruginosa
PA3646
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Pseudomonas aeruginosa

General Information

General Information Comment Organism
physiological function overexpression of UDP-3-O-[3-hydroxylauroyl] glucosamine N-acyltransferase reduces the quorum sensing regulator LasR activity, swarming motility, protease production and virulence without any influence on growth. These effects by PA3646 overexpression are caused by decreased production of quorum sensing signal Pseudomonas aeruginosa