Literature summary for 2.3.1.191 extracted from

Alshalchi, S.A.; Anderson, G.G.
Expression of the lipopolysaccharide biosynthesis gene lpxD affects biofilm formation of Pseudomonas aeruginosa (2015), Arch. Microbiol., 197, 135-145.

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Organism

Organism	UniProt	Comment	Textmining
Pseudomonas aeruginosa	Q02RB8	-	-
Pseudomonas aeruginosa UCBPP-PA14	Q02RB8	-	-

General Information

General Information	Comment	Organism
physiological function	a loss-of-expression mutant of lpxD is defective for biofilm formation on biotic and abiotic surfaces. The mutant strain exhibits significantly decreased bacterial attachment to cultured airway epithelial cells, as well as increased bacterial cytotoxicity toward airway cells. Airway cells incubated with the lpxD mutant or with mutant lipid A extracts exhibit decreased IL-8 production and necrosis, respectively	Pseudomonas aeruginosa

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Release 2023.1 (January 2023)