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Literature summary for 2.3.1.184 extracted from
- Quorum quenching: Enzymatic disruption of N-acylhomoserine lactone-mediated bacterial communication in Burkholderia thailandensis (2004), Appl. Environ. Microbiol., 70, 6173-6180.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | btaI1 and btaI3 gene disruption mutant strains cause hyper-hemolysis of sheep erythrocytes | Burkholderia thailandensis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Burkholderia thailandensis | AHSs are key enzymes of the quorum-sensing systems of Gram-negative bacteria, the quorum-sensing system of Burkholderia thailandiensis contains at least three AHL synthases and five transcriptional regulators, enzyme disruption mutant strains cause hyper-hemolysis of sheep erythrocytes | ? | - |
? |  |
| S-adenosyl-L-methionine + decanoyl-[acyl-carrier protein] | Burkholderia thailandensis | - |
5'-methylthioadenosine + N-decanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein] | - |
? | |
| S-adenosyl-L-methionine + hexanoyl-[acyl-carrier protein] | Burkholderia thailandensis | substrate of BtaI1 and BtaI3 | 5'-methylthioadenosine + N-hexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein] | - |
? | |
| S-adenosyl-L-methionine + octanoyl-[acyl-carrier protein] | Burkholderia thailandensis | substrate of BtaI1 and BtaI3 | 5'-methylthioadenosine + N-octanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein] | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Burkholderia thailandensis | - |
several isozymes, including genes btaI1 and btaI3 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | AHSs are key enzymes of the quorum-sensing systems of Gram-negative bacteria, the quorum-sensing system of Burkholderia thailandiensis contains at least three AHL synthases and five transcriptional regulators, enzyme disruption mutant strains cause hyper-hemolysis of sheep erythrocytes | Burkholderia thailandensis | ? | - |
? | |
| S-adenosyl-L-methionine + decanoyl-[acyl-carrier protein] | - |
Burkholderia thailandensis | 5'-methylthioadenosine + N-decanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein] | - |
? | |
| S-adenosyl-L-methionine + hexanoyl-[acyl-carrier protein] | substrate of BtaI1 and BtaI3 | Burkholderia thailandensis | 5'-methylthioadenosine + N-hexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein] | - |
? | |
| S-adenosyl-L-methionine + octanoyl-[acyl-carrier protein] | substrate of BtaI1 and BtaI3 | Burkholderia thailandensis | 5'-methylthioadenosine + N-octanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein] | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AHL synthase | - |
Burkholderia thailandensis |
| AHS | - |
Burkholderia thailandensis |
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Release 2023.1 (January 2023)
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