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Literature summary for 2.3.1.180 extracted from

  • Wang, J.; Kodali, S.; Lee, S.H.; Galgoci, A.; Painter, R.; Dorso, K.; Racine, F.; Motyl, M.; Hernandez, L.; Tinney, E.; Colletti, S.L.; Herath, K.; Cummings, R.; Salazar, O.; Gonzalez, I.; Basilio, A.; Vicente, F.; Genilloud, O.; Pelaez, F.; Jayasuriya, H.; Young, K.; Cully, D.F.; Singh, S.B.
    Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties (2007), Proc. Natl. Acad. Sci. USA, 104, 7612-7616.
    View publication on PubMedView publication on EuropePMC
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Inhibitors

Inhibitors Comment Organism Structure
platencin
-
 Staphylococcus aureus
platensimycin
-
 Staphylococcus aureus

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus
-
-
-

Synonyms

Synonyms Comment Organism
beta-ketoacyl-[acyl-carrier protein (ACP)] synthase III
-
 Staphylococcus aureus
FabH
-
 Staphylococcus aureus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
additional information
-
 IC50 for platencin is 0.00391 ng/ml Staphylococcus aureus additional information