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Literature summary for 2.3.1.165 extracted from

  • Petersen, L.; Holm, D.; Gotfredsen, C.; Mortensen, U.; Larsen, T.
    Investigation of a 6-MSA synthase gene cluster in Aspergillus aculeatus reveals 6-MSA-derived aculinic acid, aculins A-B and epi-Aculin A (2015), ChemBioChem, 16, 2200-2204.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Aspergillus aculeatus
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-
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + 3 malonyl-CoA + NADPH + H+
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Aspergillus aculeatus 6-methylsalicylate + 4 CoA + 3 CO2 + NADP+ + H2O
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?

Synonyms

Synonyms Comment Organism
6-MSA
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Aspergillus aculeatus
ASPAC_1904397
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Aspergillus aculeatus

General Information

General Information Comment Organism
physiological function in Aspergillus aculeatus, 6-methylsalicylic acid is incorporated into aculinic acid, which further incorporates into three compounds named aculins A and B, and epi-aculin A Aspergillus aculeatus