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Literature summary for 2.3.1.163 extracted from
- Purification and characterization of acetyl coenzyme A: 10-hydroxytaxane O-acetyltransferase from cell suspension cultures of Taxus chinensis (1999), Phytochemistry, 50, 763-774.
Application
| Application | Comment | Organism |
|---|---|---|
| pharmacology | use in synthesis of taxol for anticnacer treatment | Taxus cuspidata |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.061 | - |
acetyl-CoA | - |
Taxus cuspidata |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 70900 | - |
1 * 70900, SDS-PAGE | Taxus cuspidata |
| 71000 | - |
gel filtration | Taxus cuspidata |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + 10-desacetyltaxuyunnanin C | Taxus cuspidata | - |
CoA + taxuyunnanin C | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Taxus cuspidata | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Taxus cuspidata |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2,5,10,14-desacetyltaxuyunnanin C | - |
Taxus cuspidata | CoA + 2,5,10-desacetyltaxuyunnanin C | - |
? | |
| acetyl-CoA + 10-desacetyltaxuyunnanin C | - |
Taxus cuspidata | CoA + taxuyunnanin C | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 70900, SDS-PAGE | Taxus cuspidata |
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Release 2023.1 (January 2023)
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