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Literature summary for 2.3.1.16 extracted from

  • Staack, H.; Binstock, J.F.; Schulz, H.
    Purification and properties of a pig heart thiolase with broad chain length specificity and comparison of thiolases from pig heart and Escherichia coli (1978), J. Biol. Chem., 253, 1827-1831.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information
-
Sus scrofa
0.0018
-
3-oxodecanoyl-CoA
-
Sus scrofa
0.0024
-
3-oxooctanoyl-CoA
-
Sus scrofa
0.0083
-
3-oxohexanoyl-CoA
-
Sus scrofa
0.016
-
acetoacetyl-CoA
-
Sus scrofa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
46000
-
4 * 46000, SDS-PAGE Sus scrofa
200000
-
gel filtration Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CoA + 3-oxoacyl-CoA Sus scrofa
-
acyl-CoA + acetyl-CoA
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
heart muscle Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
597
-
-
Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CoA + 3-oxoacyl-CoA
-
Sus scrofa acyl-CoA + acetyl-CoA
-
?
CoA + 3-oxodecanoyl-CoA
-
Sus scrofa acetyl-CoA + octanoyl-CoA
-
?
CoA + 3-oxohexanoyl-CoA
-
Sus scrofa acetyl-CoA + butanoyl-CoA
-
?
CoA + 3-oxooctanoyl-CoA
-
Sus scrofa acetyl-CoA + hexanoyl-CoA
-
?
CoA + acetoacetyl-CoA
-
Sus scrofa acetyl-CoA + acetyl-CoA
-
?

Subunits

Subunits Comment Organism
tetramer 4 * 46000, SDS-PAGE Sus scrofa