Protein Variants | Comment | Organism |
---|---|---|
additional information | the starter substrates for chalcone synthase or acridone synthase reaction are placed in different topographies in the active site pocket of the enzymes. Therefore conformational changes in the periphery beyond the active site cavity volumes determine the product formation and interconversion of enzymes by mutation of the active sites is insufficient | Ruta graveolens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ruta graveolens | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
3 malonyl-CoA + N-methylanthraniloyl-CoA = 4 CoA + 1,3-dihydroxy-N-methylacridone + 3 CO2 + H2O | the starter substrates for chalcone synthase or acridone synthase reaction are placed in different topographies in the active site pocket of the enzymes. Therefore conformational changes in the periphery beyond the active site cavity volumes determine the product formation and interconversion of enzymes by mutation of the active sites is insufficient | Ruta graveolens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-methylanthraniloyl-CoA + 3 malonyl-CoA | - |
Ruta graveolens | 1,3-dihydroxy-N-methylacridone + CoA + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACS2 | - |
Ruta graveolens |